Penn State Department of Chemistry

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Schaak_CoP highlight Jensen group (PSU) and van Duyne group (Northwestern): Origin of intensity fluctuations in single-molecule tip-enhanced Raman scattering. Dana Hosko receives Wendt Award Sharon Devlin receives Wendt Award Bevilacqua Group
Dana Hosko received the Gerald Wendt Award for Excellence in Support of Research and Graduate Programs
Sharon Devlin received the Gerald Wendt Award for Excellence in Support of Research and Graduate Programs
Pallavi Thaplyal from the Bevilacqua lab led a study, reported recently in Biochemistry, demonstrating that the reaction pathway of a small RNA enzyme is dictated by the charge density of the metal ions in the reaction. DOI: 10.1021/acs.biochem.5b00190
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Chemistry Spotlights

Xin Zhang joins PSU Faculty

Xin Zhang joins PSU Faculty Xin Zhang is an assistant professor of Chemistry, Biochemistry and Molecular Biology. His research interests focus on biological chemistry and chemical biology.

Proper folding and appropriate function of the cellular proteome is essential for life. However, this process is constant challenged by stresses that dynamically alter the cellular folding environment. The Zhang lab aims to 1) develop chemical tools to monitor cellular stresses that influence protein folding in real time; 2) decipher how the energy landscapes associated with proper protein folding and function are regulated by the cellular folding environment; and 3) examine how this regulation leads to significant biological consequences. The success of this research program not only discerns the origin and consequence of the biological regulation of protein folding and function in a fashion that has not been considered to date, but also potentiates diagnosis and therapeutic strategies to human diseases that are rooted in defective protein folding and function.

Before joining the faculty at Penn State, Zhang was a postdoctoral scholar at the Scripps Research Institute. He earned a Ph.D. at the California Institute of Technology in 2010, a M.S. at the Dalian Institute of Chemical Physics, Chinese Academy of Sciences in 2004, and completed an undergraduate degree at the University of Science and Technology of China in 2001. Zhang’s awards and honors include a Burroughs Wellcome Fund Career Award at the Scientific Interface, a Helen Hay Whitney Postdoctoral Fellowship, an ACS Nobel Laureate Signature Award for Graduate Education in Chemistry, and a Caltech Herbert Newby McCoy Award in Chemistry.


Squire Booker named Howard Hughes Medical Investigator

Squire Booker named Howard Hughes Medical Investigator Squire Booker, professor of chemistry and biochemistry and molecular biology has been named a Howard Hughes Medical Investigator. Research in the Booker lab is endeavoring to understand at the detailed molecular level the reaction mechanisms employed by various enzymes, and then to exploit what we learn to impact favorably on human health and the human condition in general. View the press release which was published on 22 May 2015.


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